You or an ally is going to Grapple them you won’t be able to keep them
Each infusion which applies to an existing item also specifies that it makes the item magical. Because you must infuse a non-magical item, you can’t stack infusions on the same item, and the effects won’t stack with spells like Magic Weapon or Elemental Weapon because those spells all affect target “nonmagic weapon” and make it a magic weapon. Several of the infusions apply to existing weapons or armor. Replicate Magic Item is the only one that can be selected more than once, so expect to skip some other infusion options to get Replicate Magic multiple times. You get total of just 6 infused items by 20th level, and you’ll know 12 Infusions, which means you’ll have plenty of options to consider on any single day. The Artificer’s ability to create semi-permanent magic items gives you a ton of options.